A new splicing variant of a type III POU gene from zebrafish encodes a POU protein with a distinct C-terminal

Biochim Biophys Acta. 1998 May 11;1397(3):253-6. doi: 10.1016/s0167-4781(98)00032-3.

Abstract

A zebrafish POU protein cDNA clone was isolated and sequenced. It appears to be a novel splicing variant of the previously reported zebrafish POU gene zp-12. There are four splicing variants and at least three of them lead to different C-terminal amino acid sequences. The four splicing variants are differentially regulated during development, indicating that they may be functionally diversified.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing
  • Amino Acid Sequence
  • Animals
  • Base Sequence
  • Cloning, Molecular
  • DNA, Complementary / genetics
  • DNA-Binding Proteins / chemistry
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / metabolism
  • Gene Expression Regulation, Developmental
  • Genetic Variation
  • Molecular Sequence Data
  • POU Domain Factors
  • Transcription Factors / chemistry
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism
  • Zebrafish / genetics*
  • Zebrafish / growth & development
  • Zebrafish / metabolism

Substances

  • DNA, Complementary
  • DNA-Binding Proteins
  • POU Domain Factors
  • Transcription Factors

Associated data

  • GENBANK/AF039952