Abstract
A zebrafish POU protein cDNA clone was isolated and sequenced. It appears to be a novel splicing variant of the previously reported zebrafish POU gene zp-12. There are four splicing variants and at least three of them lead to different C-terminal amino acid sequences. The four splicing variants are differentially regulated during development, indicating that they may be functionally diversified.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alternative Splicing
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Amino Acid Sequence
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Animals
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Base Sequence
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Cloning, Molecular
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DNA, Complementary / genetics
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DNA-Binding Proteins / chemistry
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DNA-Binding Proteins / genetics*
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DNA-Binding Proteins / metabolism
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Gene Expression Regulation, Developmental
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Genetic Variation
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Molecular Sequence Data
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POU Domain Factors
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Transcription Factors / chemistry
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Transcription Factors / genetics*
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Transcription Factors / metabolism
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Zebrafish / genetics*
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Zebrafish / growth & development
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Zebrafish / metabolism
Substances
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DNA, Complementary
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DNA-Binding Proteins
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POU Domain Factors
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Transcription Factors