[The modulating effects of preparations of Baikal skullcap (Scutellaria baicalensis) on erythron reactions under conditions of neurotic exposures]

Eksp Klin Farmakol. 1998 Jan-Feb;61(1):37-9.
[Article in Russian]

Abstract

Preparations of Scutellaria baicalensis, namely its dry extract and the bioflavonoid baicalin stimulate erythropoiesis depressed in deprivation of the paradoxical phase of sleep. After a conflict situation, when hemopoiesis is activated, both drugs normalize it. The modulating effect of drugs on hemopoiesis in exposure to neurotic factors is a consequence of their influence on the functional state of the cell elements of the hemopoiesis-inducing microenvironment. The capacity of the Scutellaria baicalensis drugs for reducing the effect of psychoemotional stress on the blood system is apparently related to their influence on the adrenergic structures.

Publication types

  • English Abstract

MeSH terms

  • Animals
  • Bone Marrow Cells / drug effects
  • Disease Models, Animal
  • Drug Evaluation, Preclinical
  • Erythropoiesis / drug effects*
  • Flavonoids / pharmacology
  • Flavonoids / therapeutic use
  • Male
  • Mice
  • Mice, Inbred CBA
  • Neurotic Disorders / blood
  • Neurotic Disorders / drug therapy*
  • Neurotic Disorders / etiology
  • Plant Extracts / pharmacology
  • Plant Extracts / therapeutic use
  • Plants, Medicinal / chemistry*
  • Stimulation, Chemical

Substances

  • Flavonoids
  • Plant Extracts
  • baicalin