Measuring contrast sensitivity in aretinopathic patients with Insulin Dependent Diabetes Mellitus

Doc Ophthalmol. 1996;93(3):199-209. doi: 10.1007/BF02569060.

Abstract

Contrast sensitivity measurements were obtained from 66 patients with Insulin Dependent Diabetes Mellitus (IDDM) and no visible diabetic retinopathy (Group A, n = 30 prepubescent and pubescent subjects; Group B, n = 36 postpubescent subjects). Contrast thresholds were determined for stationary and 6.87 Hz phase-alternating gratings at eight spatial frequencies from 0.18 to 15.7 c/deg. Data from each group of diabetic patients was compared with data from puberty-matched normal subjects. Mean value of the last four determinations of glycohemoglobin Alc (HbAlc) was used as a index of glycemic control. We found that patients with IDDM and no retinopathy had normal contrast sensitivity and that contrast thresholds were not significantly related to sexual maturity, duration of diabetes and glycemic control.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Blood Glucose / metabolism
  • Child
  • Chromatography, High Pressure Liquid
  • Contrast Sensitivity*
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / physiopathology*
  • Diabetic Retinopathy / blood
  • Diabetic Retinopathy / physiopathology
  • Female
  • Follow-Up Studies
  • Glycated Hemoglobin / metabolism
  • Humans
  • Male
  • Puberty / physiology
  • Random Allocation
  • Sensory Thresholds

Substances

  • Blood Glucose
  • Glycated Hemoglobin A