Malyngamides M and N from the Hawaiian Red Alga Gracilaria coronopifolia

Y Kan; T Fujita; H Nagai; B Sakamoto; Y Hokama

doi:10.1021/np970423n

Malyngamides M and N from the Hawaiian Red Alga Gracilaria coronopifolia

J Nat Prod. 1998 Jan 23;61(1):152-5. doi: 10.1021/np970423n.

Authors

Y Kan¹, T Fujita, H Nagai, B Sakamoto, Y Hokama

Affiliation

¹ Suntory Institute for Bioorganic Research, Wakayamadai, Shimamoto, Mishima-gun, Osaka 618, Japan, and John A. Burns School of Medicine, University of Hawaii at Manoa, Honolulu, Hawaii 96822.

PMID: 9548841
DOI: 10.1021/np970423n

Abstract

Two new malyngamides, M and N (1, 2), were isolated along with malyngamide I acetate (3) from the Hawaiian red alga Gracilaria coronopifolia. Our results suggest that malyngamide N (2) is a revised structure of deacetoxystylocheilamide (5). The absolute configuration of malyngamide I acetate was deduced to be 3 using the reversed octant rule.