[Gene Nc73EF of Drosophila melanogaster encodes a protein highly homologous to E1 subunit of human 2-oxoglutarate dehydrogenase]

N E Gruntenko; A V Kochetov; K S Makarova; V P Mishin; V V Lukasheva; A A Ptitsyn; V A Kokoza

[Gene Nc73EF of Drosophila melanogaster encodes a protein highly homologous to E1 subunit of human 2-oxoglutarate dehydrogenase]

Genetika. 1998 Jan;34(1):32-7.

[Article in Russian]

Authors

N E Gruntenko¹, A V Kochetov, K S Makarova, V P Mishin, V V Lukasheva, A A Ptitsyn, V A Kokoza

Affiliation

¹ Institute of Cytology and Genetics, Russian Academy of Sciences, Novosibirsk, Russia.

PMID: 9532450

Abstract

The primary structure of the cDNA copy of the evolutionary conserved gene Nc73EF from the region 73EF of Drosophila melanogaster was determined. Gene Nc73EF was shown to encode a protein highly homologous to the E1 subunit of human 2-oxoglutarate dehydrogenase, which catalyzes one of the key reactions of the Krebs cycle.

Publication types

English Abstract

MeSH terms

Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
Catalysis
Citric Acid Cycle
Conserved Sequence*
Drosophila melanogaster / genetics*
Genes, Insect*
Genetic Code
Humans
Ketoglutarate Dehydrogenase Complex / genetics*
Molecular Sequence Data
Sequence Homology, Amino Acid
Sequence Homology, Nucleic Acid

Substances

Ketoglutarate Dehydrogenase Complex