Epidermolysis bullosa acquisita localized to the face

J Dermatol. 1998 Jan;25(1):19-22. doi: 10.1111/j.1346-8138.1998.tb02339.x.

Abstract

A 39-year-old woman had a three-year history of recurrent bullous eruption localized to her left cheek. The diagnosis of epidermolysis bullosa acquisita was confirmed by means of direct immunofluorescence and direct immunoelectron microscopic studies performed on the perilesional salt-split skin. Topical corticosteroid treatment reduced pruritus and bullae formation. This case of localized epidermolysis bullosa acquisita on the face is reminiscent of Brunsting-Perry cicatricial pemphigoid. We also review the previously reported cases of localized epidermolysis bullosa acquisita.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Administration, Topical
  • Adult
  • Anti-Inflammatory Agents / therapeutic use
  • Blister / drug therapy
  • Complement C3 / analysis
  • Diagnosis, Differential
  • Eosinophils / pathology
  • Epidermolysis Bullosa Acquisita / drug therapy
  • Epidermolysis Bullosa Acquisita / pathology*
  • Facial Dermatoses / drug therapy
  • Facial Dermatoses / pathology*
  • Female
  • Fluorescent Antibody Technique, Direct
  • Follow-Up Studies
  • Glucocorticoids
  • Humans
  • Immunoglobulin G / analysis
  • Microscopy, Immunoelectron
  • Neutrophils / pathology
  • Pemphigoid, Benign Mucous Membrane / diagnosis
  • Pruritus / drug therapy
  • Recurrence

Substances

  • Anti-Inflammatory Agents
  • Complement C3
  • Glucocorticoids
  • Immunoglobulin G