208 patients between the age of 1 month to 56 years, with symptoms of respiratory tract allergy were investigated. In all cases serum titre of sIgE to birch, thymoty, rye, mugwort pollen, Alternaria Alternata, dog, cat fur, Dermatophagoides pteronyssinus and farinae was determined with the use of Quidel immunoenzymatic method. We have found sIgE to Alternaria Alternata in 8 (38%), birch pollen in 5 (23.8%) dog fur in 5 (23.8%) and thymoty and rye pollen in 3 (14.3%) even among one years-old infants. In the second and third years of life allergy to dog fur, Alternaria Alternata and pollen of birch, thymoty and rye increases while the age of 4 and 5 is less significant, later (6-10 years old patients) increases again. Among teenagers pollinosis gets decreases and adults have development constant level of the disease.