Introduction: Pleomorphic hyalinizing angiectasic tumor of soft parts is a recently described tumor of adults showing low malignant potential.
Material and methods: We describe the case of a 80 yr-old woman with a palpable mass located in the subcutis of the right popliteal fossa. Tissue was formalin-fixed and processed as routine. Sections were stained with Hematoxylin-Eosin. In addition, the lesion was studied with histochemical stainings for mucins and immunocytochemistry.
Results: The lesion was well-circumscribed by a fibrous pseudocapsule and was composed mostly by short strands of spindle cells with pleomorphic nuclei and several vessels surrounded by hyalinized material. Necrosis and mitoses were absent. Neoplastic cells immunoreacted with anti-Qbend antiserum (CD34).
Discussion: Pleomorphic hyalinizing angiectatic tumor of soft parts was distinguished from solitary fibrous tumor. A common origin of these lesions is proposed.