[Malignant tumors of the peripheral nerve sheath (MPNST) after irradiation]

Pathologica. 1997 Aug;89(4):441-5.
[Article in Italian]

Abstract

A case of relapsed malignant tumor of the brachial plexus and its nervous roots (MPNST) was observed in a patient treated with radiotherapy for Hodgkin's disease 24 years previously. A known risk of radiation therapy is the induction of secondary neoplasms, less commonly malignant peripheral nerve sheath tumor (MPNST). The clinico-pathological features of this rare tumor are presented and the possible relationship between radiotherapy and MPNST is discussed.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adolescent
  • Brachial Plexus / pathology*
  • Fatal Outcome
  • Female
  • Hodgkin Disease / radiotherapy*
  • Humans
  • Lymphatic Irradiation / adverse effects*
  • Magnetic Resonance Imaging
  • Mediastinal Neoplasms / pathology
  • Mediastinal Neoplasms / secondary
  • Neoplasm Recurrence, Local / pathology
  • Neoplasms, Radiation-Induced / etiology*
  • Neoplasms, Radiation-Induced / pathology
  • Neoplasms, Second Primary / etiology*
  • Neoplasms, Second Primary / pathology
  • Neurofibrosarcoma / etiology*
  • Neurofibrosarcoma / pathology
  • Neurofibrosarcoma / secondary
  • Spinal Cord Compression / etiology
  • Spinal Neoplasms / complications
  • Spinal Neoplasms / pathology
  • Spinal Neoplasms / secondary