The Institute of oncology represents an oncological center which renders the measures of prevention, early detection and diagnostic of tumours and multidisciplinary strategy for antitumour treatment, including rehabilitation of patients suffering from tumours. To fulfil the above mentioned aims the Institute is organized in ten completely operative units and several functional centres and committees. The paper presents only few aspects of diagnostic and treatment of tumour, and the implementation of the programmes and targets of individual organizational units within the Institute. This orientation is particularly actual now when epidemiological studies show an increase of disease and mortality incidence in the region of Vojvodina.