Candida albicans suppresses transcription of melanogenesis enzymes in cultured melanocytes

Mycoses. 1997 Dec;40(9-10):373-5. doi: 10.1111/j.1439-0507.1997.tb00253.x.

Abstract

Human skin can be colonized by different yeasts that may have an impact on skin pigmentation. In order to study this effect normal human melanocytes were cultured with different yeasts. Reverse transcription polymerase chain reaction (RT-PCR) analysis gives evidence that Candida albicans suppresses the transcription of melanogenesis enzymes.

MeSH terms

  • Aldose-Ketose Isomerases*
  • Candida albicans / physiology*
  • Cells, Cultured
  • Fungal Proteins / genetics
  • Humans
  • Melanocytes / enzymology*
  • Melanocytes / microbiology*
  • Monophenol Monooxygenase / genetics
  • Polymerase Chain Reaction
  • Skin Pigmentation / genetics*
  • Transcription, Genetic*

Substances

  • Fungal Proteins
  • Monophenol Monooxygenase
  • Aldose-Ketose Isomerases