In 837 birds which died or were euthanatized because of their disease, blood could be taken within 12 hours before death. Blood chemistry results were compared with specific necropsy findings of different organs. The parameters aspartate aminotransferase (AST), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), creatinine kinase (CK), glutamate dehydrogenase (GLDH), glucose, total protein, uric acid, urea and creatinine were measured. Possible reasons for the bad comparability of blood chemistry results and organ lesions are discussed. Glucose and creatinine were found not to be useful in a routine panel for avian patients.