A comprehensive dynamical model of pulsatile secretion of the hypothalamo-pituitary-gonadal axis in man

Comput Biol Med. 1997 Nov;27(6):507-13. doi: 10.1016/s0010-4825(97)00026-7.

Abstract

We proposed a comprehensive dynamical model for the hormone secretion of the hypothalamo-pituitary-gonadal axis in man. This model is comprehensive and more reasonable than any previous model. A large number of deductions of this model agree well with experimental results.

MeSH terms

  • Albumins / metabolism
  • Algorithms
  • Cell Division
  • Gonadal Steroid Hormones / metabolism*
  • Gonadotropin-Releasing Hormone / metabolism
  • Humans
  • Hypothalamo-Hypophyseal System / metabolism*
  • Leydig Cells / cytology
  • Leydig Cells / metabolism
  • Luteinizing Hormone / metabolism
  • Male
  • Models, Biological*
  • Pulsatile Flow
  • Sex Hormone-Binding Globulin / metabolism
  • Testis / cytology
  • Testis / metabolism*
  • Testosterone / metabolism

Substances

  • Albumins
  • Gonadal Steroid Hormones
  • Sex Hormone-Binding Globulin
  • Gonadotropin-Releasing Hormone
  • Testosterone
  • Luteinizing Hormone