Antihelminthic drugs in diffuse unilateral subacute neuroretinitis

Am J Ophthalmol. 1998 Jan;125(1):109-11. doi: 10.1016/s0002-9394(99)80248-7.

Abstract

Purpose: To evaluate the efficacy of ivermectin and thiabendazole in confirmed cases of diffuse unilateral subacute neuroretinitis.

Methods: Two patients with diffuse unilateral subacute neuroretinitis were treated with anthelminthic drugs. The first patient was treated with ivermectin and the second, with thiabendazole.

Results: The worms were still mobile after treatment with ivermectin or thiabendazole. With the application of photocoagulation, the organisms were destroyed, and the patients' vision improved.

Conclusion: In these two patients, ivermectin and thiabendazole were not effective in treating confirmed diffuse unilateral subacute neuroretinitis.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adolescent
  • Adult
  • Anthelmintics / therapeutic use*
  • Eye Infections, Parasitic / parasitology
  • Eye Infections, Parasitic / pathology
  • Eye Infections, Parasitic / therapy*
  • Female
  • Fundus Oculi
  • Humans
  • Ivermectin / therapeutic use
  • Laser Coagulation*
  • Male
  • Optic Neuritis / parasitology
  • Optic Neuritis / pathology
  • Optic Neuritis / therapy*
  • Protozoan Infections / parasitology
  • Protozoan Infections / pathology
  • Protozoan Infections / therapy*
  • Retina / parasitology
  • Retinitis / parasitology
  • Retinitis / pathology
  • Retinitis / therapy*
  • Thiabendazole / therapeutic use
  • Visual Acuity

Substances

  • Anthelmintics
  • Ivermectin
  • Thiabendazole