Kawasaki's disease is a systemic vasculitis typical of infancy that affects children under five years old. Given that it is important to make an early diagnosis and to start prompt treatment of this disease owing to possible cardiac complications, even in the long term, the authors felt it important to report a number of cases referred to their attention in order to underline the polymorphism of onset. The symptoms that are considered to be typical of the disease, namely fever, laterocervical adenopathy, alterations of the extremities, polymorphous rash, orolabial modifications, conjunctival hyperemia, can often be masked by the symptoms provoked by the possible involvement of all the organs and apparatuses.