Fibrolamellar hepatocellular carcinoma: results of partial liver resection

Rev Esp Enferm Dig. 1997 Sep;89(9):699-705.
[Article in English, Spanish]

Abstract

Aim: To assess the results of partial hepatic resection in the treatment of fibrolamellar hepatocellular carcinoma.

Patients and results: We present six cases of Fibrolamellar hepatocellular carcinoma treated by partial hepatic resection. There were five females and one male with a mean age of 20 (2.6) yr. Five patients were stage IVA and 1 IVB based on the Union International Against Cancer Classification. Two patients, due to recurrent disease, needed further pulmonary resection and a hilar lymphadenectomy. All six cases underwent major resection, three with vascular reconstruction. No operative mortality was recorded; half of the patients displayed some degree of morbidity. One patient died six months after the operation and the rest are alive at 78, 41, 24, 12 and 9 months. We believe that even in advanced cases, an aggressive surgical policy even with vascular reconstruction is justified in patients with fibrolamellar hepatocellular carcinoma.

MeSH terms

  • Adolescent
  • Adult
  • Carcinoma, Hepatocellular / mortality
  • Carcinoma, Hepatocellular / pathology
  • Carcinoma, Hepatocellular / surgery*
  • Female
  • Follow-Up Studies
  • Hepatectomy / methods*
  • Humans
  • Liver Neoplasms / mortality
  • Liver Neoplasms / pathology
  • Liver Neoplasms / surgery*
  • Male
  • Neoplasm Recurrence, Local / epidemiology
  • Neoplasm Staging
  • Postoperative Complications / epidemiology