Protoporphyrin derivatives--the use in localization of neoplasmas by titanium laser-induced fluorescence technique

M Kwaśny; Z Mierczyk; P Fiedor; W Rowiński; K Socha; A Graczyk; J Domaniecki; A P Mazurek

Protoporphyrin derivatives--the use in localization of neoplasmas by titanium laser-induced fluorescence technique

Acta Pol Pharm. 1997 Mar-Apr;54(2):123-8.

Authors

M Kwaśny¹, Z Mierczyk, P Fiedor, W Rowiński, K Socha, A Graczyk, J Domaniecki, A P Mazurek

Affiliation

¹ Optoelectronics Institute, Technical Military Academy, Warsaw, Poland.

PMID: 9415203

Abstract

Examples of in vivo detection of skin neoplasmas (Mercl, melanoma) and breast carcinoma using laser induced fluorescence (LIF) and bis-1[1-alanylo-N]-ethylodeuteroporphyrin (Ala-PP) are described in this study. Photosensitizer, wave titanium laser and standard CCD camera coupled to vision amplifier enable precise neoplasm imaging, Ala-PP retention monitoring and further photodynamic therapy (PDT).

Publication types

Comparative Study

MeSH terms

Breast Neoplasms / diagnosis*
Carcinoma / diagnosis*
Carcinoma, Merkel Cell / diagnosis
Female
Hematoporphyrin Photoradiation
Humans
Lasers*
Melanoma / diagnosis*
Protoporphyrins* / chemistry
Skin Neoplasms / diagnosis*
Spectrometry, Fluorescence

Substances

Protoporphyrins