Abstract
An 11-year-old male castrated Persian cat with spontaneous hyperadrenocorticism was presented. Both adrenals were grossly enlarged and calcified. A diagnosis of pituitary-dependent hyperadrenocorticism was made. Signs of hyperadrenocorticism resolved with long-term mitotane treatment. Concurrent diabetes mellitus resolved after 220 days of therapy. No severe adverse drug reactions were noted.
MeSH terms
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Adrenal Cortex / diagnostic imaging
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Adrenal Cortex / pathology
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Adrenocortical Hyperfunction / drug therapy
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Adrenocortical Hyperfunction / pathology
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Adrenocortical Hyperfunction / veterinary*
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Animals
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Antineoplastic Agents, Hormonal / therapeutic use*
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Blood Glucose / analysis
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Cat Diseases / blood
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Cat Diseases / drug therapy*
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Cat Diseases / pathology
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Cats
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Diabetes Mellitus / blood
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Diabetes Mellitus / drug therapy
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Diabetes Mellitus / veterinary
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Dose-Response Relationship, Drug
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Hydrocortisone / blood
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Insulin / therapeutic use
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Male
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Mitotane / therapeutic use*
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Radiography
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Time Factors
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Ultrasonography
Substances
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Antineoplastic Agents, Hormonal
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Blood Glucose
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Insulin
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Mitotane
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Hydrocortisone