In-laboratory removal of femoral sheath following protamine administration in patients having intracoronary stent implantation

Am J Cardiol. 1997 Nov 15;80(10):1336-8. doi: 10.1016/s0002-9149(97)00676-0.

Abstract

Two hundred twenty-eight patients with successful coronary stent implantation were randomized either to protamine administration and femoral sheath removal (group I, n = 117) or no heparin neutralization and delayed sheath removal (group II, n = 111). The hospital stay after treatment was shorter in patients receiving protamine; therefore, protamine use for neutralizing circulating heparin may be safely administered immediately after stent implantation.

Publication types

  • Clinical Trial
  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Anticoagulants / therapeutic use
  • Coronary Disease / therapy*
  • Dalteparin / therapeutic use
  • Female
  • Femoral Artery
  • Hemorrhage / prevention & control
  • Heparin / therapeutic use
  • Heparin Antagonists / therapeutic use*
  • Humans
  • Male
  • Middle Aged
  • Premedication
  • Protamines / therapeutic use*
  • Stents*
  • Thrombosis / prevention & control

Substances

  • Anticoagulants
  • Heparin Antagonists
  • Protamines
  • Heparin
  • Dalteparin