Extended duration between harvest and re-infusion of human bone marrow stored at room temperature

J H Lipton; N Jamal; H A Messner

doi:10.1038/sj.bmt.1700984

Extended duration between harvest and re-infusion of human bone marrow stored at room temperature

Bone Marrow Transplant. 1997 Nov;20(9):785-6. doi: 10.1038/sj.bmt.1700984.

Authors

J H Lipton¹, N Jamal, H A Messner

Affiliation

¹ Department of Medicine, Princess Margaret Hospital/Ontario Cancer Institute, University of Toronto, Canada.

PMID: 9384482
DOI: 10.1038/sj.bmt.1700984

Abstract

A major limitation of unrelated bone marrow transplantation is the duration of time that is safe between harvest and re-infusion of the marrow. We have been able to demonstrate safe re-infusion of bone marrow kept at room temperature during transport, after almost 36 h. In vitro colony-forming assays suggest that stability may be as long as 5 days.

Publication types

Case Reports

MeSH terms

Adult
Blood Specimen Collection / methods*
Bone Marrow Transplantation*
Humans
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / therapy
Male
Specimen Handling / methods
Temperature
Time Factors