Abstract
We report our experience with ten virgin cases (5 children, 5 adults) with coccidioidal meningitis treated with fluconazole. The diagnosis was confirmed by a positive culture of the cerebrospinal fluid. Fluconazole at doses of 6/mg/kg/day for children and 400 mg/day for adults were given. All responded well, in five it was discontinued and four relapsed but responded well to fluconazole. We conclude that fluconazole is useful for coccidioidal meningitis.
MeSH terms
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Adolescent
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Adult
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Antifungal Agents / therapeutic use*
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Child
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Child, Preschool
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Coccidioidomycosis / cerebrospinal fluid
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Coccidioidomycosis / diagnosis
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Coccidioidomycosis / drug therapy*
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Drug Evaluation
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Female
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Fluconazole / therapeutic use*
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Humans
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Male
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Meningitis, Fungal / cerebrospinal fluid
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Meningitis, Fungal / diagnosis
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Meningitis, Fungal / drug therapy*
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Middle Aged
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Retrospective Studies
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Treatment Outcome
Substances
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Antifungal Agents
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Fluconazole