Abstract
This review aims at describing the influence of established and not yet sufficiently characterized parameters on the prognosis of thyroid follicle cell carcinomas. The analysis of literature data covers a broad spectrum of pathologic and biologic factors from classical prognostic features like age, gender and tumor stage to mutation, activation or, where applicable, inactivation of tumor suppressor genes, metastasis-related genes and adhesion molecules.
Publication types
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English Abstract
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adenocarcinoma, Follicular / classification
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Adenocarcinoma, Follicular / genetics
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Adenocarcinoma, Follicular / pathology
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Biomarkers, Tumor / genetics
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Carcinoma / classification
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Carcinoma / genetics
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Carcinoma / pathology
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Carcinoma, Medullary / classification
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Carcinoma, Medullary / genetics
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Carcinoma, Medullary / pathology
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Carcinoma, Papillary / classification
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Carcinoma, Papillary / genetics
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Carcinoma, Papillary / pathology
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DNA Mutational Analysis
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Genes, Tumor Suppressor / genetics
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Humans
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Prognosis
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Thyroid Gland / pathology
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Thyroid Neoplasms / classification
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Thyroid Neoplasms / genetics
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Thyroid Neoplasms / pathology*