Changing concepts in fibrinolysis

Curr Opin Hematol. 1995 Sep;2(5):345-50. doi: 10.1097/00062752-199502050-00004.

Abstract

New advances in molecular biology have prompted reevaluation of traditional concepts in fibrinolysis. Identification of novel cell surface activation receptors as well as a series of plasminogen/apolipoprotein(a) homologues suggests new potential mechanisms for controlled generation of the multifunctional protease plasmin.

Publication types

  • Review

MeSH terms

  • Animals
  • Animals, Genetically Modified
  • Annexin A2 / physiology
  • Carrier Proteins / physiology
  • Fibrin / physiology
  • Fibrinolysis / physiology*
  • HMGB1 Protein
  • High Mobility Group Proteins / physiology
  • Humans
  • Kringles
  • Receptors, Cell Surface / physiology

Substances

  • Annexin A2
  • Carrier Proteins
  • HMGB1 Protein
  • High Mobility Group Proteins
  • Receptors, Cell Surface
  • Fibrin