An unusual poisoning with the unusual pesticide amitraz

Hum Exp Toxicol. 1997 Oct;16(10):600-1. doi: 10.1177/096032719701601008.

Abstract

Amitraz, 1,5 di-(2,4-dimethylphenyl)-3-methyl-1,3,5-triaza-penta-1,4-diene, a formamidine pesticide, is used worldwide. It causes side-effects in animals that resemble those caused by pure alpha 2-adrenergic agonist drugs such as clonidine. Data on poisonings in humans are scanty. We report on a case of human poisoning with amitraz with typical signs of alpha 2-adrenoreceptor stimulation.

Publication types

  • Case Reports

MeSH terms

  • Blood Pressure / drug effects
  • Bradycardia / chemically induced
  • Coma / chemically induced
  • Heart Rate / drug effects
  • Humans
  • Insecticides / poisoning*
  • Male
  • Middle Aged
  • Receptors, Adrenergic, alpha-2 / drug effects
  • Toluidines / blood
  • Toluidines / pharmacokinetics
  • Toluidines / poisoning*

Substances

  • Insecticides
  • Receptors, Adrenergic, alpha-2
  • Toluidines
  • amitraz