Moderate beer consumption and positive biochemical changes in patients with coronary atherosclerosis

J Intern Med. 1997 Sep;242(3):219-24. doi: 10.1046/j.1365-2796.1997.00195.x.

Abstract

Objectives: The aim of this study was to evaluate the influence of moderate beer consumption on lipid metabolism and antioxidant activity in patients (pts) with coronary artery disease (CAD).

Subjects: Forty-eight male pts with CAD not alcohol beverages consumers were randomly divided into experimental (EG) and control (CG) groups, 24 pts each.

Setting: Rehovot University Hospital, Israel.

Intervention: Every patient of the EG during a period of 30 consecutive days consumed 330 ml of Maccabee beer (> 20 g of alcohol). The pts of the CG did not consume alcohol during the trial period.

Methods: A wide range of tests including total cholesterol, LDL-C, HDL-C, total tocopherol and alpha-tocopherol.

Results: Only in the pts of the EG were found a tendency to an increase of the level of HDL-C and a statistically significant rise in the level of total tocopherol (P < 0.025) and alpha-tocopherol (P < 0.025).

Conclusions: Even a short period of moderate beer consumption leads to some favourable biochemical changes in blood of pts with CAD which are widely regarded as indicators of CAD prevention.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alcohol Drinking*
  • Beer*
  • Cholesterol / blood
  • Coronary Artery Disease / blood*
  • Humans
  • Lipid Peroxidation*
  • Lipids / blood*
  • Male
  • Prospective Studies
  • Treatment Outcome
  • Triglycerides / blood
  • Vitamin E / blood*

Substances

  • Lipids
  • Triglycerides
  • Vitamin E
  • Cholesterol