EGF-receptor tyrosine kinase and 12-lipoxygenase activity regulate expression of 12-lipoxygenase in human tumor cells

Adv Exp Med Biol. 1997:407:9-14. doi: 10.1007/978-1-4899-1813-0_2.
No abstract available

MeSH terms

  • Arachidonate 12-Lipoxygenase / biosynthesis*
  • Arachidonate 12-Lipoxygenase / genetics
  • Biotin / analogs & derivatives
  • Biotin / pharmacology
  • Carcinoma, Squamous Cell / pathology
  • Enzyme Induction / drug effects
  • Enzyme Inhibitors / pharmacology
  • Epidermal Growth Factor / pharmacology*
  • ErbB Receptors / antagonists & inhibitors
  • ErbB Receptors / physiology*
  • Gene Expression Regulation, Neoplastic / drug effects*
  • Humans
  • Neoplasm Proteins / biosynthesis
  • Neoplasm Proteins / genetics
  • Neoplasm Proteins / physiology*
  • Phalloidine / analogs & derivatives
  • Phalloidine / pharmacology
  • Phthalimides / pharmacology
  • Polymerase Chain Reaction
  • RNA, Messenger / biosynthesis
  • RNA, Messenger / genetics
  • Signal Transduction / drug effects
  • Tumor Cells, Cultured

Substances

  • Enzyme Inhibitors
  • Neoplasm Proteins
  • Phthalimides
  • RNA, Messenger
  • 4-(3-(biotinylaminohexamethylenaminocarbonyl)propanoylaminomethyl)-2-methyl-1,3-dithiolane-2-yl-(Ala(7))phalloidin
  • Phalloidine
  • Epidermal Growth Factor
  • Biotin
  • Arachidonate 12-Lipoxygenase
  • ErbB Receptors
  • 4,5-dianilinophthalimide