Archaeal introns: splicing, intercellular mobility and evolution

Trends Biochem Sci. 1997 Sep;22(9):326-31. doi: 10.1016/s0968-0004(97)01113-4.

Abstract

Until recently, it appeared that archaeal introns were spliced by a process specific to the archaeal domain in which an endoribonuclease cuts a 'bulge-helix-bulge' motif that forms at exon-intron junctions. Recent results, however, have shown that the endoribonuclease involved in archaeal intron splicing is a homologue of two subunits of the enzyme complex that excises eukaryotic nuclear tRNA introns. Moreover, some archaeal introns encode homing enzymes that are also encoded by group I introns.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Archaea / genetics*
  • Archaea / metabolism
  • Evolution, Molecular
  • Introns*
  • Models, Molecular
  • Nucleic Acid Conformation
  • Phylogeny
  • RNA Splicing
  • RNA, Bacterial / chemistry
  • RNA, Bacterial / genetics
  • RNA, Transfer / chemistry
  • RNA, Transfer / genetics

Substances

  • RNA, Bacterial
  • RNA, Transfer