DGLA discoordinately suppresses IL-1 induced metalloproteinase mRNA levels in human synovial fibroblasts

Inflamm Res. 1997 Aug:46 Suppl 2:S124-6. doi: 10.1007/s000110050137.
No abstract available

MeSH terms

  • 8,11,14-Eicosatrienoic Acid / pharmacology*
  • Arthritis, Rheumatoid / enzymology*
  • Blotting, Northern
  • Collagenases / genetics
  • Fibroblasts / enzymology*
  • Humans
  • Interleukin-1 / pharmacology*
  • Matrix Metalloproteinase 3 / genetics
  • Metalloendopeptidases / genetics*
  • RNA, Messenger / metabolism*
  • Synovial Membrane / cytology*

Substances

  • Interleukin-1
  • RNA, Messenger
  • Collagenases
  • Metalloendopeptidases
  • Matrix Metalloproteinase 3
  • 8,11,14-Eicosatrienoic Acid