Abstract
The immunological and genetic properties of Francisella tularensis vaccine strain are discussion with regard to its use to produce recombinant vaccines. This bacterium-based vector is supposed to be an excellent object for investigating the role of protective antigens in the development of immunity against intracellular bacteria.
MeSH terms
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Animals
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Antigens, Bacterial / immunology
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Bacterial Vaccines / genetics
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Bacterial Vaccines / immunology*
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Bacterial Vaccines / therapeutic use
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Francisella tularensis / genetics
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Francisella tularensis / immunology*
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Humans
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Immunity
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Tularemia / immunology
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Tularemia / prevention & control*
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Vaccines, Synthetic / immunology*
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Virulence / drug effects
Substances
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Antigens, Bacterial
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Bacterial Vaccines
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Vaccines, Synthetic