Abstract
The role of galanin in memory paradigms has been largely evaluated. The galanin-antagonist galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C-terminal fragment of bradykinin, has been found to improve social memory in 'social recognition' test when i.c.v. administered at doses varying from 6-6000 nmoles.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Cognition / drug effects
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Cues
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Galanin / analogs & derivatives*
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Galanin / pharmacology
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Injections, Intraventricular
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Male
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Memory / drug effects*
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Rats
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Rats, Wistar
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Social Behavior*
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Substance P / analogs & derivatives*
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Substance P / pharmacology
Substances
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galantide
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Substance P
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Galanin