[Experimental bases of the use of pharmacologic agents aimed at higher heat resistance of humans as means of individual protection]

Med Tr Prom Ekol. 1997:(5):35-8.
[Article in Russian]

Abstract

A group of volunteers was exposed to action of heating microclimate (ambient temperature 30 +/- 1 degrees C, relative humidity 35 +/- 5%) and other critical occupation factors (physical loading, personal protective equipment). They received simultaneously one of the medicines: placebo, bemethyl (0.5 g), phenibut (0.25 g), obsidan (0.08 g), or phenibut (0.25 g) combined with obsidan (0.08 g). Combined phenibut (0.25 g) with obsidan (0.08 g) were proved to be the most effective method to increase stability of the human body against studying critical occupational factors.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adjuvants, Immunologic / pharmacology*
  • Anti-Anxiety Agents / administration & dosage
  • Anti-Anxiety Agents / pharmacology*
  • Benzimidazoles / pharmacology*
  • Body Temperature Regulation / drug effects*
  • Hot Temperature*
  • Humans
  • Microclimate
  • Occupational Health*
  • Propranolol / administration & dosage
  • Propranolol / pharmacology*
  • Tranquilizing Agents / administration & dosage
  • Tranquilizing Agents / pharmacology*
  • gamma-Aminobutyric Acid / administration & dosage
  • gamma-Aminobutyric Acid / analogs & derivatives*
  • gamma-Aminobutyric Acid / pharmacology

Substances

  • Adjuvants, Immunologic
  • Anti-Anxiety Agents
  • Benzimidazoles
  • Tranquilizing Agents
  • gamma-Aminobutyric Acid
  • bemethyl
  • Propranolol
  • 4-amino-3-phenylbutyric acid