Functional aspects of Aujeszky's disease (pseudorabies) viral proteins with relation to invasion, virulence and immunogenicity

Abstract

In the present review, the interaction of Aujeszky's disease (pseudorabies) virus (ADV) with individual susceptible cells and the entire host is presented. Special emphasis is put on how viral envelope glycoproteins control invasion and virulence. Furthermore, the importance of envelope glycoproteins in the induction of a protective immunity is discussed.