Purpose: To report the clinicopathologic findings of a myxoma that arose in the subepithelial region of the right cornea of a 53-year-old man 4 years after successful treatment of an infectious corneal ulcer.
Methods: Histopathologic and histochemical evaluation of corneal tissue.
Results: This rare lesion appears to have originated from corneal stromal fibroblasts that reacted to an inflammatory stimulus and produced excessive amounts of glycosaminoglycans (hyaluronic acid) rather than normal collagen.
Conclusion: Myxoma formation may require interruption of Bowman's layer and proximity of the scar to the epithelium.