Abstract
Azathioprine and rheumatoid arthritis are known to be associated with an increased risk of the development of non-Hodgkin's lymphoma; however, the manifestation of fulminant hepatic failure is extremely uncommon in patients with non-Hodgkin's lymphoma. In this article, we describe a patient with rheumatoid arthritis who was taking azathioprine, in whom fulminant hepatic failure occurred because of massive lymphomatous infiltration of the liver.
MeSH terms
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Antirheumatic Agents / adverse effects*
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Antirheumatic Agents / therapeutic use
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Arthritis, Rheumatoid / drug therapy
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Azathioprine / adverse effects*
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Azathioprine / therapeutic use
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Chemical and Drug Induced Liver Injury / complications
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Chemical and Drug Induced Liver Injury / etiology*
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Fatal Outcome
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Female
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Humans
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Liver Neoplasms / chemically induced*
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Liver Neoplasms / diagnostic imaging
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Liver Neoplasms / pathology
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Lymphoma, Large-Cell, Anaplastic / chemically induced*
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Lymphoma, Large-Cell, Anaplastic / diagnostic imaging
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Lymphoma, Large-Cell, Anaplastic / pathology
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Middle Aged
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Ultrasonography
Substances
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Antirheumatic Agents
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Azathioprine