Search for herpesvirus DNA in cerebrospinal fluid of HIV patients with brain disorders: prevalence of cytomegalovirus DNA findings

M Portolani; M Meacci; A M Sabbatini; P Pietrosemoli; M Pecorari; C Cermelli; B De Rienzo

doi:10.3109/13550289709018293

Search for herpesvirus DNA in cerebrospinal fluid of HIV patients with brain disorders: prevalence of cytomegalovirus DNA findings

J Neurovirol. 1997 Jun;3(3):192-6. doi: 10.3109/13550289709018293.

Authors

M Portolani¹, M Meacci, A M Sabbatini, P Pietrosemoli, M Pecorari, C Cermelli, B De Rienzo

Affiliation

¹ Department of Biomedical Sciences, University of Modena, Italy.

PMID: 9200066
DOI: 10.3109/13550289709018293

Abstract

A study was carried out to search for the presence of the seven human herpesvirus DNAs in cerebrospinal fluid from 52 human immunodeficiency virus-infected patients with brain disorders. Cytomegalovirus DNA was the most prevalent with 12 positive samples; Epstein-Barr virus and varicellazoster DNAs were detected in three and two samples, respectively, while no sample was positive for the DNA of the other herpesviruses.

MeSH terms

AIDS Dementia Complex / cerebrospinal fluid*
AIDS Dementia Complex / complications
AIDS Dementia Complex / virology*
AIDS-Related Opportunistic Infections / cerebrospinal fluid*
AIDS-Related Opportunistic Infections / virology
Cytomegalovirus / isolation & purification*
Cytomegalovirus Infections / cerebrospinal fluid
Cytomegalovirus Infections / etiology
DNA Primers
DNA, Viral / cerebrospinal fluid*
Herpesviridae Infections / cerebrospinal fluid*
Herpesviridae Infections / etiology
Herpesvirus 3, Human / isolation & purification*
Herpesvirus 4, Human / isolation & purification*
Humans
Polymerase Chain Reaction

Substances

DNA Primers
DNA, Viral