An assessment of medium power semi-conductor laser treatment effectiveness was evaluated in 205 patients (132 females and 73 males) aged 57 to 75 (mean 62.5) years with pain syndrome in a course of hip, knee, shoulder, elbow, temporo-maxillaris and vertebral joints degenerative changes. Procedures were performed 3 times a week using punctual technique, sweeping and scanning. Total number of procedures ranged from 8 to 20 and radiation energy dose was 4 to 12 J/cm2. Favourable therapy effect was demonstrated as pain and oedema disappearance in about 40% of patients; insignificant therapeutic effect was achieved in 46.3% and lack of affect in 13.7% of individuals.