Wegener's presenting as submandibular swelling

Sarcoidosis Vasc Diffuse Lung Dis. 1997 Mar;14(1):81-2.

Abstract

We describe a patient in whom bilateral swelling of submandibular glands was the initial manifestation of limited Wegener's disease. The diagnosis was based on positive anti-neutrophil cytoplasmic antibody [C-ANCA], dense inflammatory infiltrate predominantly of lymphocytes in submandibular glands, presence of non-caseating ill-formed granulomas in transbronchial biopsy and resolution of symptoms following immuno-suppressive treatment.

Publication types

  • Case Reports

MeSH terms

  • Antibodies, Antineutrophil Cytoplasmic / analysis
  • Biopsy
  • Bronchoscopy
  • Granulomatosis with Polyangiitis / complications*
  • Granulomatosis with Polyangiitis / diagnosis
  • Granulomatosis with Polyangiitis / drug therapy
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Male
  • Middle Aged
  • Salivary Gland Diseases / complications*
  • Salivary Gland Diseases / diagnosis
  • Salivary Gland Diseases / drug therapy
  • Submandibular Gland / diagnostic imaging
  • Submandibular Gland / pathology*
  • Tomography, X-Ray Computed

Substances

  • Antibodies, Antineutrophil Cytoplasmic
  • Immunosuppressive Agents