Candida norvegensis: a fluconazole-resistant species

Antimicrob Agents Chemother. 1997 Jun;41(6):1375-6. doi: 10.1128/AAC.41.6.1375.

Abstract

Candida norvegensis has been an unusual cause of infections in humans. In Norway this species was isolated from eight patients from 1990 to 1996 and was of probable pathogenic significance in four of them. All isolates were resistant to fluconazole. The same was true for two C. norvegensis isolates from before 1940, and it is therefore assumed that the fluconazole resistance is inherent.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Amphotericin B / pharmacology
  • Antifungal Agents / pharmacology*
  • Candida / drug effects*
  • Candidiasis / microbiology
  • Drug Resistance, Microbial
  • Fluconazole / pharmacology*
  • Flucytosine / pharmacology
  • Humans
  • Itraconazole / pharmacology
  • Microbial Sensitivity Tests
  • Middle Aged

Substances

  • Antifungal Agents
  • Itraconazole
  • Amphotericin B
  • Fluconazole
  • Flucytosine