Abstract
Twelve patients with liver cirrhosis complaining of painful muscle cramps were treated with Niuche-Shen-Qi-Wan (TJ-107). Three patients were at the decompensated state. Muscle cramps disappeared in 4 weeks on the average after oral administration of TJ-107 in all 12 patients. During the period of TJ-107 administration, there was no significant improvement of hepatic function. One patient complained of mild epigastric discomfort after taking TJ-107, but there were no other adverse effects. Our results indicate that TJ-107 is useful for treatment of painful muscle cramps in cirrhotic patients.
Publication types
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Case Reports
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Clinical Trial
MeSH terms
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Administration, Oral
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Aged
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Anti-Inflammatory Agents, Non-Steroidal / administration & dosage
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology
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Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
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Cholagogues and Choleretics / pharmacology
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Cholagogues and Choleretics / therapeutic use
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Diuretics / administration & dosage
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Diuretics / therapeutic use
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Drugs, Chinese Herbal / administration & dosage
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Drugs, Chinese Herbal / pharmacology
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Drugs, Chinese Herbal / therapeutic use*
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Female
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Humans
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Liver Cirrhosis / complications
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Liver Cirrhosis / drug therapy*
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Liver Cirrhosis / physiopathology
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Male
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Middle Aged
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Muscle Cramp / drug therapy*
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Muscle Cramp / etiology
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology
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Plant Extracts / therapeutic use
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Plants, Medicinal / metabolism
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Treatment Outcome
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Ursodeoxycholic Acid / administration & dosage
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Ursodeoxycholic Acid / therapeutic use
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Vitamin B Complex / administration & dosage
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Vitamin B Complex / therapeutic use
Substances
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Anti-Inflammatory Agents, Non-Steroidal
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Cholagogues and Choleretics
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Diuretics
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Drugs, Chinese Herbal
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Plant Extracts
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sairei-to
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Vitamin B Complex
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saiko-keishi-to
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Ursodeoxycholic Acid