Abstract
Recent observations cast doubt on the view that cytotoxic T cells play a key role in keeping HIV-1 infection in check, and that it is the decline in this mechanism of immune surveillance that permits progression to AIDS.
MeSH terms
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Acquired Immunodeficiency Syndrome / immunology*
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Acquired Immunodeficiency Syndrome / virology
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Anti-HIV Agents / pharmacology
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Anti-HIV Agents / therapeutic use
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Disease Progression
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HIV Infections / drug therapy
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HIV Infections / immunology
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HIV Infections / pathology
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HIV Infections / virology
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HIV-1 / drug effects
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HIV-1 / immunology
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HIV-1 / physiology
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Humans
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Immunologic Surveillance*
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Models, Immunological
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RNA, Viral / blood
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T-Lymphocytes, Cytotoxic / immunology*
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Viremia / drug therapy
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Viremia / virology
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Virus Replication
Substances
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Anti-HIV Agents
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RNA, Viral