Validity of the 13-C-urea breath test for the diagnosis of Helicobacter pylori infection

M Kajiwara; K Iida; K Takatori; Y Taniguchi; K Kimura

doi:10.1248/cpb.45.741

Validity of the 13-C-urea breath test for the diagnosis of Helicobacter pylori infection

Chem Pharm Bull (Tokyo). 1997 Apr;45(4):741-3. doi: 10.1248/cpb.45.741.

Authors

M Kajiwara¹, K Iida, K Takatori, Y Taniguchi, K Kimura

Affiliation

¹ Dept. of Medicinal Chemistry, Meiji College of Pharmacy, Tokyo, Japan.

PMID: 9145510
DOI: 10.1248/cpb.45.741

Abstract

Infection with Helicobacter pylori (H. pylori) plays an important role in the pathogenesis of gastritis, peptic ulcer and gastric cancer, and the 13C-urea breath test (13C-UBT) is a convenient and non-invasive method for the detection of H. pylori in the stomach. We have examined the sensitivity, specificity and accuracy of 13C-UBT. The 13CO2/12CO2 ratio was measured using infrared spectroscopy (IR) and gas chromatography/mass spectrometry (GC-MS).

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Breath Tests / methods
Gas Chromatography-Mass Spectrometry
Helicobacter Infections / diagnosis*
Helicobacter pylori*
Humans
Reproducibility of Results
Sensitivity and Specificity
Spectrophotometry, Infrared