Idiopathic eosinophilic myositis associated with vasculitis and symmetrical polyneuropathy

Br J Rheumatol. 1997 Feb;36(2):276-9. doi: 10.1093/rheumatology/36.2.276.

Abstract

We present a 79-yr-old white woman admitted to the hospital with diffuse myalgias and muscle weakness associated with eosinophilia. Examination of a muscle biopsy section revealed eosinophilic myositis with vasculitis. This association is infrequent and we describe the first case report with symmetrical polyneuropathy. The treatment with prednisone (60 mg/day) led to a complete clinical-pathological recovery of the disease. We review the differential diagnosis and the aetiopathogenic mechanism.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aged
  • Anti-Inflammatory Agents / therapeutic use
  • Diagnosis, Differential
  • Eosinophilia / complications*
  • Eosinophilia / drug therapy
  • Eosinophilia / pathology
  • Female
  • Humans
  • Muscle, Skeletal / pathology
  • Myositis / complications*
  • Myositis / drug therapy
  • Myositis / pathology
  • Peripheral Nervous System Diseases / complications*
  • Peripheral Nervous System Diseases / drug therapy
  • Peripheral Nervous System Diseases / pathology
  • Prednisolone / therapeutic use
  • Vasculitis / complications*
  • Vasculitis / drug therapy
  • Vasculitis / pathology

Substances

  • Anti-Inflammatory Agents
  • Prednisolone