Abstract
Familial atrial myxomas may present as a component of the Carney complex, an autosomal dominant multiple neoplasia and lentiginosis syndrome. Although a gene defect for the Carney complex in some families maps to chromosome 2p, this syndrome is genetically heterogeneous, and other genetic loci also produce familial atrial myxomas.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Adult
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Child
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Chromosomes, Human, Pair 2
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Female
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Genetic Heterogeneity
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Heart Atria
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Heart Neoplasms / genetics*
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Humans
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Lod Score
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Male
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Middle Aged
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Myxoma / genetics*
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Neoplastic Syndromes, Hereditary / genetics*
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Pedigree
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Risk Factors