[Eradication of Helicobacter pylori in patients with recurrent abdominal pain using a triple drug treatment]

Rev Gastroenterol Mex. 1996 Oct-Dec;61(4):310-3.
[Article in Spanish]

Abstract

Background: Different antibiotics, antagonist H2 and others have been used for elimination and/or eradication of Helicobacter pylori.

Aims: Evaluate elimination of Helicobacter pylori with amoxicillin, bismuth subsalicylate and ranitidine; and the improvement of recurrent abdominal pain.

Method: 20 children with recurrent abdominal pain associated to gastritis and histologic identification of Helicobacter pylori were studied under a period of 18 months (January 1992 to June 1993), at Instituto Nacional de Pediatría, México, D.F. All children were treated simultaneously with: Amoxicillin, 15 days, plus ranitidine and bismuth subsalicylate for one month.

Results: Helicobacter pylori was eliminated in 14 of 20 children studied. All these children had an important improvement of recurrent abdominal pain.

Conclusion: Elimination of Helicobacter pylori and clinical improvement was present in 14 of 20 children studied (70%).

Publication types

  • Comparative Study

MeSH terms

  • Abdominal Pain / drug therapy*
  • Amoxicillin / administration & dosage*
  • Amoxicillin / pharmacology
  • Anti-Ulcer Agents / administration & dosage*
  • Anti-Ulcer Agents / pharmacology
  • Bismuth / administration & dosage*
  • Bismuth / pharmacology
  • Child
  • Female
  • Helicobacter Infections / drug therapy*
  • Helicobacter pylori / drug effects*
  • Humans
  • Longitudinal Studies
  • Male
  • Organometallic Compounds / administration & dosage*
  • Organometallic Compounds / pharmacology
  • Penicillins / administration & dosage*
  • Penicillins / pharmacology
  • Prospective Studies
  • Ranitidine / administration & dosage*
  • Ranitidine / pharmacology
  • Recurrence
  • Salicylates / administration & dosage*
  • Salicylates / pharmacology

Substances

  • Anti-Ulcer Agents
  • Organometallic Compounds
  • Penicillins
  • Salicylates
  • bismuth subsalicylate
  • Amoxicillin
  • Ranitidine
  • Bismuth