Relation between decline in FEV1 and exposure to dust and tobacco smoke in aluminium potroom workers

Occup Environ Med. 1997 Jan;54(1):27-31. doi: 10.1136/oem.54.1.27.

Abstract

Objectives: To investigate the relation between pulmonary function and occupational exposure in aluminium pot operators.

Methods: 2795 observations were obtained in 630 workers over six years of follow up. An autoregressive method of analysis was used.

Results: After adjustment for FEV1 in the three previous years, the effect of smoking v no smoking on FEV1 was -43.1 ml, 95% confidence interval (95% CI) -72.3 to -13.9. Similarly, an increase in the exposure to particulates by 1 mg/m3 corresponded to a decrease in FEV1 of -11.9 ml, 95% CI -19.9 to -3.9. Age was a significant predictor of both FEV1 and FVC.

Conclusion: Exposure to particulates in aluminium potrooms seems to increase the decline in FEV15 thereby increasing the risk of development of chronic obstructive lung disease in pot operators.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aluminum
  • Confidence Intervals
  • Dust / adverse effects*
  • Female
  • Fluorides / adverse effects
  • Forced Expiratory Volume / physiology*
  • Humans
  • Longitudinal Studies
  • Male
  • Metallurgy*
  • Middle Aged
  • Occupational Exposure / adverse effects*
  • Regression Analysis
  • Respiration Disorders / etiology*
  • Respiration Disorders / physiopathology
  • Smoking / adverse effects*
  • Smoking / physiopathology
  • Vital Capacity

Substances

  • Dust
  • Aluminum
  • Fluorides