Pseudo-felty's syndrome. Report of a case with no symptoms for at least 15 years

Rev Rhum Engl Ed. 1996 Jan;63(1):56-8.

Abstract

The prognosis of large granular lymphocyte proliferation with rheumatoid arthritis (pseudo-Felty's syndrome) remains uncertain. We report a case with a 15-year follow-up. To date, the patient has not developed lymphadenopathy, splenomegaly, abnormalities in erythrocyte or platelet counts, neutropenia or severe or unexplained infections. This favorable course is not ascribable to an unusual lymphocyte phenotype (CD3+, CD8+, CD57+). A beneficial effect of methotrexate therapy is possible.

Publication types

  • Case Reports

MeSH terms

  • Antirheumatic Agents / administration & dosage
  • Antirheumatic Agents / therapeutic use
  • Arthritis, Rheumatoid / diagnosis
  • Arthritis, Rheumatoid / drug therapy
  • Arthritis, Rheumatoid / physiopathology
  • Diagnosis, Differential
  • Felty Syndrome / diagnosis*
  • Felty Syndrome / drug therapy
  • Felty Syndrome / physiopathology
  • Female
  • Granulocytes / immunology
  • Humans
  • Middle Aged
  • Receptors, Antigen, T-Cell / immunology*
  • T-Lymphocytes / immunology*

Substances

  • Antirheumatic Agents
  • Receptors, Antigen, T-Cell