Control of cerebral and ocular blood flow autoregulation in neonates

Pediatr Clin North Am. 1997 Feb;44(1):137-52. doi: 10.1016/s0031-3955(05)70467-3.

Abstract

Several factors have been implicated in the regulation of cerebral and ocular vasomotor tone in the newborn: the interrelationship between prostanoids, NO, and other vasoactive mediators remains a subject of interest and active investigation. Pharmacologic modulation may provide new treatment modalities for diseases of the newborn that are mostly hemodynamic and vascular in nature.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Cerebral Hemorrhage / drug therapy*
  • Cerebral Hemorrhage / physiopathology
  • Cerebral Ventricles*
  • Cerebrovascular Circulation / drug effects*
  • Eye / blood supply*
  • Eye / innervation
  • Homeostasis / drug effects*
  • Humans
  • Infant, Newborn
  • Infant, Premature, Diseases / drug therapy*
  • Infant, Premature, Diseases / physiopathology
  • Nitric Oxide / physiology
  • Prostaglandins / physiology
  • Retinopathy of Prematurity / drug therapy*
  • Retinopathy of Prematurity / physiopathology

Substances

  • Prostaglandins
  • Nitric Oxide