[Diagnosis of Epstein-Barr virus-associated gastric carcinoma and its background gastric mucosa]

Nihon Rinsho. 1997 Feb;55(2):374-80.
[Article in Japanese]

Abstract

Recently, the presence of Epstein-Barr virus(EBV) in almost 7% of gastric carcinoma lesions was reported. From our observation, EBV-associated gastric carcinomas located mainly in the gastric body, and moderate to poorly differentiated adenocarcinoma with lymphoid infiltration, as currently reported. Macroscopically, there were mainly thick and ulcerated lesions, EBV-associated gastric carcinomas had close relation with intestinal metaplasia, and EBV could be suspected to provide the immortalized epithelial cells.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / pathology
  • Gastric Mucosa / pathology
  • Herpesviridae Infections / pathology*
  • Herpesvirus 4, Human / isolation & purification*
  • Humans
  • Stomach Neoplasms / diagnosis*
  • Stomach Neoplasms / pathology
  • Tumor Virus Infections / pathology*