Phosprenyl: a novel drug with antiviral and immunomodulatory activity

Arch Immunol Ther Exp (Warsz). 1996;44(5-6):395-400.

Abstract

A novel antiviral drug with immunomodulatory activity (Phosprenyl) is presented. The main active ingredient of the preparation is polyprenyl phosphates. This medicine is highly efficient against a number of viruses, including HIV in vitro, and tick-borne encephalitis and rabies viruses in the experimental models in vivo. In veterinary practice Phosprenyl is now regarded as an effective therapeutic means for treatment of canine distemper, hepatitis, enteritis, etc.

Publication types

  • Review

MeSH terms

  • Adjuvants, Immunologic* / chemistry
  • Adjuvants, Immunologic* / pharmacology
  • Adjuvants, Immunologic* / therapeutic use
  • Animals
  • Antiviral Agents* / chemistry
  • Antiviral Agents* / pharmacology
  • Antiviral Agents* / therapeutic use
  • Clinical Trials as Topic
  • Cricetinae
  • Distemper / drug therapy
  • Dog Diseases / drug therapy*
  • Dogs
  • Dolichol Phosphates / physiology
  • Drug Evaluation, Preclinical
  • Enteritis / drug therapy
  • Enteritis / veterinary
  • Hepatitis, Viral, Animal / drug therapy
  • Mice
  • Molecular Structure
  • Parvoviridae Infections / drug therapy
  • Parvoviridae Infections / veterinary
  • Polyisoprenyl Phosphates* / chemistry
  • Polyisoprenyl Phosphates* / pharmacology
  • Polyisoprenyl Phosphates* / therapeutic use
  • Rats
  • Virus Diseases / drug therapy
  • Virus Diseases / veterinary*

Substances

  • Adjuvants, Immunologic
  • Antiviral Agents
  • Dolichol Phosphates
  • Polyisoprenyl Phosphates
  • phosprenyl
  • dolichol monophosphate