Immunohistological study of IgA, IgG and IgM in endoscopic biopsies of dogs with plasmacytic-lymphocytic colitis

Zentralbl Veterinarmed B. 1996 Dec;43(10):613-20. doi: 10.1111/j.1439-0450.1996.tb00360.x.

Abstract

The results of a histological and immunohistochemical study of endoscopic colon biopsies of dogs with plasmacytic-lymphocytic colitis are reported. The histological study revealed that a characteristic infiltrate rich in lymphocytes and plasma cells was seen within the lamina propria in all the biopsies. The immunohistochemical investigation suggests that IgG is the major antibody in the immune response of dogs with plasmacytic-lymphocytic colitis.

MeSH terms

  • Animals
  • Biopsy / methods
  • Biopsy / veterinary
  • Colitis / immunology
  • Colitis / pathology
  • Colitis / veterinary*
  • Colon / immunology
  • Colon / pathology*
  • Dog Diseases / immunology*
  • Dog Diseases / metabolism
  • Dog Diseases / pathology
  • Dogs
  • Endoscopy, Gastrointestinal / methods
  • Endoscopy, Gastrointestinal / veterinary
  • Female
  • Immunoglobulin A / analysis*
  • Immunoglobulin A / metabolism
  • Immunoglobulin G / analysis*
  • Immunoglobulin G / metabolism
  • Immunoglobulin M / analysis*
  • Immunoglobulin M / metabolism
  • Immunohistochemistry
  • Lymphocytes / immunology
  • Lymphocytes / pathology
  • Male
  • Plasma Cells / immunology
  • Plasma Cells / pathology

Substances

  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M